Bpsbioscience/UBE2K（UBC1），His标签/79373/10µg
商品编号：
79373
品牌：
bpsbioscience
市场价：
¥6200.00
美元价：
3720.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.colicells
MW:25kDa
Genbank#:NM_005339
Tag(s):N-terminalHis-tag
Background:
UBE2KalsoknownasUBC1orubiquitin-conjugatingenzymeE2Kbelongstotheubiquitin-conjugatingenzymefamilywhichinteractswithRINGfingerproteins.UBE2Kcanubiquitinatehuntingtin,thegeneproductforHuntington"sdisease.Huntingtinisubiquitinatedinperipheralcells,suggestingaroleforUBE2Kinthedegradationofhuntingtin(1).UBE2Kplaysaroleinaggregateformationofexpandedpolyglutamineproteinsandthesuppressionofapoptosisinpolyglutaminediseases(2).UBE2KalsoplaysaroleinthedislocationofnewlysynthesizedMHCclassIheavychainsfromtheendoplasmicreticulum,andinvolvementinfoamcellformation.
Description:
RecombinantfulllengthUBE2K(UBC1)proteinalsoknownasE2-25K,HIP2,HYPG,LIG,andUB1.GenbankAccessionNM_005339,withanN-terminalHis-tag,expressedinE.colicells.MW=25kDa.
Synonym(s):
E2-25K,HIP2,HYPG,LIG,UBC1
Formulation:
50mMsodiumphosphate,pH7.0,300mMNaCl,150mMimidazole,0.1mMPMSF,0.25mMDTT,25%glycerol.
Storage/StABIlity:
Atleast6monthsat–80°C.Avoidfreeze/thawcycles.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Kalchman,M.A.et.al.J.Biol.Chem.271:19385-19394,1996.
2.DePril,R.etal.MolCellNeurosci.2007Jan;34(1):10-9.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Ubiquitination
ProductType:
ActivatingEnzyme
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
