Bpsbioscience/UBE2E3 (UBCH9), His-Tag/79371/10 µg
商品编号：
79371
品牌：
bpsbioscience
市场价：
¥6200.00
美元价：
3720.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.colicells
MW:25kDa
Genbank#:NM_006357
Tag(s):N-terminalHis-tag
Background:
UBE2E3alsoknownasUBCH9orubiquitin-conjugatingenzymeE2E3isamemberoftheE2ubiquitin-conjugatingenzymefamily.Ubiquitination,thecovalentattachmentoftheproteinubiquitin(Ub)toothercellularproteinsisanimportantcellularmechanismfortargetingabnormalorshort-livedproteinsfordegradationthatinvolvesatleastthreeclassesofenzymes:ubiquitin-activatingenzymes,orE1s,ubiquitin-conjugatingenzymes,orE2s,andubiquitin-proteinligases,orE3s(1).UBE2E3ishighlyexpressedinskeletalmuscle(2).UBE2E3isessentialfortheproliferationofRPE-1cellsandisdownregulatedduringRPElayermaturationinthedevelopingmouseeye.ThesefindingsindicatethatUBE2E3isamajorenzymeinmodulatingthebalancebetweenRPEcellproliferationanddifferentiation.
Description:
RecombinantfulllengthhumanUBE2E3,alsoknownasUBCH9andUbcM2.GenbankAccessionNM_006357,withanN-terminalHis-tag,expressedinE.colicells.MW=25kDa.
Synonym(s):
UBCH9,UbcM2
Formulation:
50mMsodiumphosphate,pH7.0,300mMNaCl,150mMimidazole,0.1mMPMSF,0.25mMDTT,25%glycerol.
Storage/StABIlity:
Atleast6monthsat–80°C.Avoidfreeze/thawcycles.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Matuschewski,K.,et.al.J.Biol.Chem.271:2789-2794,1996.
2.Ito,K., et.al.Cytogenet. CellGenet.84:99-104,1999.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Ubiquitination
ProductType:
ActivatingEnzyme
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
