Bpsbioscience/SRPK1，GST标签/40277/10µg
商品编号：
40277
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:130kDa
Genbank#:BC038292
Tag(s):N-terminalGST-tag
a.a:fulllength
Background:
SRPK1isaSer/ThrproteinkinasethathassequenceandfunctionsimilartoSRPK2.Inhumancancercells,itwasobservedthatinactivationofSRPK1inducescellularresistancetoanticancerdrugssuchascisplatinandbleomycin(1).SRPK1phosphorylatesserine/arginine-rich(SR)proteins,suchassplicingfactorsASF/SF2,SC35,andSRp55,intheirarginine/serine-rich(RS)domainsinvitro.HenceitisbelievedthatSRPK1playsakeyroleinregulationofbothconstitutiveandalternativesplicingbyregulatingintracellularlocalizationofsplicingfactors(2).
Description:
Recombinanthumanserine/argininedomainproteinkinase1(SRPK1),fulllength,withN-terminalGST-tag,expressedbySf9insectcellsviaabaculovirusexpressionsystem.
Synonym(s):
SFRSK1
Purity:
≥75%
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1mMEGTA,0.1mMEDTA,0.1mMPMSF,25%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Hayes,G.M.etal:Serine-arginineproteinkinase1overexpressionisassociatedwithtumOrigenicimbalanceinmitogen-activatedproteinkinasepathwaysinbreast,colonic,andpancreaticcarcinomas.CancerRes.2007;67(5):2072-80.
2.Gui,J.-F.etal:Aserinekinaseregulatesintracellularlocalizationofsplicingfactorsinthecellcycle.Nature369:678-682,1994.
2.Gui,J.-F.etal:Aserinekinaseregulatesintracellularlocalizationofsplicingfactorsinthecellcycle.Nature369:678-682,1994.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
