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当前位置: 首页 > 产品中心 > Routine_cell_strain > Bpsbioscience/TDO-HEK293重组细胞系/60534/2小瓶
商品详细Bpsbioscience/TDO-HEK293重组细胞系/60534/2小瓶
Bpsbioscience/TDO-HEK293重组细胞系/60534/2小瓶
Bpsbioscience/TDO-HEK293重组细胞系/60534/2小瓶
商品编号: 60534
品牌: bpsbioscience
市场价: ¥176000.00
美元价: 105600.00
产地: 美国(厂家直采)
公司:
产品分类: 常规细胞株
公司分类: Routine_cell_strain
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Background:
L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions. Tryptophan 2,3 dioxygenase (TDO), is upregulated in many tumors, providing cancer cells with an avenue for immune evasion.
Description:

Stable recombinant HEK293 cell line expressing human tryptophan 2,3 dioxygenase (TDO2, TDO, TPH2, TRPO), Genbank accession number NM_005651.

Synonym(s):
tryptophan 2,3 dioxygenase, TDO2, TDO, TPH2, TRPO
Host Cell line:
HEK293
Mycoplasma Testing:
The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma-Aldrich) to confirm the absence of Mycoplasma species.
Storage / Stability:
Immediately upon receipt, store vials in liquid nitrogen
Application(s):
Monitor TDO pathway activity. Screen for activators or inhibitors of TDO in a cellular context
Reference(s):

1. Liu, X., et al., Blood. 2010; 115(17): 3520-3530.

Notes:

Contact us for pricing.

License Disclosure:Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. BPS does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact sales@bpsbioscience.com for details. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.

Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Immunotherapy
Product Type:
Cell Line
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。