Bpsbioscience/TDO抑制剂筛选分析试剂盒(384)/72036/384反应
商品编号:
72036
品牌:
bpsbioscience
市场价:
¥21400.00
美元价:
12840.00
产品分类:
其它检测试剂盒
公司分类:
Other_kits
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Background:
L-tryptophan(L-Trp)isanessentialaminoacidnecessaryforproteinsynthesisinmammaliancellsandtheL-Trptokynurenine(Kyn)pathwayisfirmlyestablishedasakeyregulatorofinnateandadaptiveimmunity.CatabolismofL-TrptoKynmaintainsanimmunosuppressivemicroenvironmentbystarvingimmunecellsofL-TrpandreleasingdegradationproductsofL-Trpthathaveimmunosuppressivefunctions.Tryptophan2,3dioxygenase(TDO)isupregulatedinmanytumors,providingcancercellswithanavenueforimmuneevasion.
Description:
TheTDOInhibitorScreeningAssayKitisdesignedtomeasureTDOenzymeinhibition.TheTDOInhibitorScreeningAssayKitissimpletouse.InhibitorandenzymeareaddedtoasamplecontainingL-Trpsubstrate.Afteraroomtemperatureincubation,activityismeasuredbymeasuringtheabsorptionofreactionproductat=320-325nm.
Synonym(s):
TDO2,tryptophan2,3dioxygenase
SuppliedAs:
Thekitcomesinaconvenientformat,withenoughreactionsolutionandenzymetoperformatotalof400reactions.
Contraindications:
DMSO>1%,strongacidsorbases,ionicdetergents,highsalt
Format:
COMPONENTS:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
UsefulforthestudyofTDOenzymology,screeninginhibitorsandselectivityprofiling.
Reference(s):
Li,J.S.,etal.Arch.InsectBiochem.Physiol.2007Feb;64(2):74–87.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Immunotherapy
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。