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Bpsbioscience/PD-1:PD-L1/PD-L2 Cell-Based Inhibitor Screening Assay Kit/60800/100 reactions
Bpsbioscience/PD-1:PD-L1/PD-L2 Cell-Based Inhibitor Screening Assay Kit/60800/100 reactions
商品编号：
60800
品牌：
bpsbioscience
市场价：
¥21400.00
美元价：
12840.00
产品分类：
常规细胞株
公司分类：
Routine_cell_strain
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
ProgrammedCellDeathProtein1(PD-1)isareceptorwhichisexpressedonactivatedT-cells.BindingofPD-1toitsligands,PD-L1andPD-L2,negativelyregulatesimmuneresponses.ThePD-1ligandsarefoundonmostcancers,andPD-1:PD-L1/2interactioninhibitsTcellactivityandallowscancercellstoescapeimmunesurveillance.
Description:
ThePD-1/PD-L1InhibitorScreeningCell-BasedAssayisabioluminescentcell-basedassaythatcanbeusedtoscreenandprofileinhibitorsofPD-1:PD-L1orPD-1:PD-L2interaction.Theassayconsistsoftwomaincomponents:•PD-1Effectorcells(PD-1/NFATreporter-Jurkatcells):ReporterJurkatTcellsexpressingfireflyluciferasegeneunderthecontrolofNFATresponseelementsandalsoconstitutivelyexpressinghumanPD-1.Thesecryopreservedcellsareprovidedinathaw-and-useformatthatdoesnotrequirecellpropagation.•ExpressionvectorsforTCRactivator,humanPD-L1,andhumanPD-L2:Transfection-readyvectorsareusedtotransfectcellstocreatethetargetcellsthatoverexpressPD-L1orPD-L2andanengineeredcellsurfaceTcellreceptor(TCR)activator.
Synonym(s):
Programmedcelldeath1,PDCD1,PD-1,PD1,SLEB2,CD279,HPD-L,ProgrammedCellDeath1Ligand1,PDL1,PD-L1,B7homolog1,B7H1,B7-H1,CD274,PDCD1L1,ProgrammedCellDeath2Ligand2,PDL2,PD-L2,CD273,PDCDL1G2,B7-DC
Format:
COMPONENTS:
Storage/StABIlity:
Storecelllineinliquidnitrogenimmediatelyuponreceipt.Storeothercomponentsasdescribedbelow.Stableforatleast6monthsfromdateofreceiptwhenstoredasdirected.
Application(s):
ScreenforactivatorsorinhibitorsofPD-1signalinginacellularcontext,•CharacterizetheBIOLOGicalactivityofPD-1anditsinteractionswithligands
ScientificCategory:
Immunotherapy
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
