Bpsbioscience/MST3，GST标签/40133/10µg
商品编号：
40133
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:63kDa
Genbank#:NM_001032296
Tag(s):N-terminalGST-tag
a.a:1–311
Background:
MST3orMammalianSterile20-likekinase3isamemberofthegerminalcenterkinase-IIIfamily.MST3containsaconservedkinasedomainatitsNH(2)-terminusandaregulatorydomainatitsCOOH-terminus.Caspase-mediatedcleavageoftheregulatorydomainofMST3activatesitsintrinsickinaseactivityandleadstonucleartranslocation.ExpressionofCOOH-terminaltruncatedMST3incellsresultsinDNAfragmentationandinductionofapoptosis(1).MST3caninhibitcellmigrationinafashiondependentonautophosphorylationandcanregulatepaxillinphosphorylationthroughtyrosinephosphatasePTP-PEST(2).
Description:
RecombinanthumanMST3(a.a.1-311),withN-terminalGST-tag,expressedbySf9insectcellsviaabaculovirusexpressionsystem.
Synonym(s):
STK24,MST-3,STK3,MST3B,RP11-111L24.5
Purity:
≥75%
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1mMEGTA,0.1mMEDTA,0.1mMPMSF,25%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Huang,CY.etal:Caspaseactivationofmammaliansterile20-likekinase3(Mst3).Nucleartranslocationandinductionofapoptosis.JBiolChem.2002Sep13;277(37):34367-74.
2.Lu,TJ.:InhibitionofCellMigrationbyAutophosphorylatedMammalianSterile20-LikeKinase3(MST3)InvolvesPaxillinandProtein-tyrosinePhosphatase-PEST.JBiolChem.2006Dec15;281(50):38405-17.
2.Lu,TJ.:InhibitionofCellMigrationbyAutophosphorylatedMammalianSterile20-LikeKinase3(MST3)InvolvesPaxillinandProtein-tyrosinePhosphatase-PEST.JBiolChem.2006Dec15;281(50):38405-17.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
