Bpsbioscience/U0126/27012/5 mg
商品编号：
27012
品牌：
bpsbioscience
市场价：
¥5000.00
美元价：
3000.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:380.5Da
CASRegistry#:109511-58-2
Formula:C18H16N6S2
Description:
U0126isaselectiveinhibitorofmitogen-activatedproteinkinasekinases,MEK-1andMEK-2.ItisaweakinhibitorofPKC,Raf,ERK,JNK,MEKK,MKK-3,MKK-4/SEK,MKK-6,Abl,Cdk2andCdk4.
Purity:
≥99%byHPLC
BIOLOGicalActivity:
U0126antagonizesAP-1transcriptionalactivityvianoncompetitiveinhibitionofthedualspecificitykinaseMEKwithIC50of0.07µMforMEK1and0.06µMforMEK2.
Solubility:
SolubleinDMSOat200mg/ml.Itispoorlysolubleinethanolandwater.
Format:
Whitetooff-whitecrystallinesolid;granularorpowder.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Favata,M.R.,etal.,J.Biol.Chem.1998;273:18623–18632.
2.DeSilva,D.R.,etal.,J.Immunol.1998;160:4175–4181.
3.Scherle,P.A.,etal.,J.Immunol.1998;161:5681–5686.
ApplicationReference(s):
1. Targetingantigen-independentproliferationinchroniclymphocyticleukemiathroughdifferentialkinaseinhibition(2017)
ScientificCategory:
Kinase
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
