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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/Noggin/90256-2/50µg
商品详细Bpsbioscience/Noggin/90256-2/50µg
Bpsbioscience/Noggin/90256-2/50µg
Bpsbioscience/Noggin/90256-2/50µg
商品编号: 90256-2
品牌: bpsbioscience
市场价: ¥7500.00
美元价: 4500.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
HostSpecies:FreeStyle293-Fcells
MW:28kDa
Genbank#:NM_005450
Tag(s):none
a.a:28–232(end)
Background:
NogginisoneofagroupofproteinsthatactassecretedantagoNISTsofBMPactivity.BMPsareessentialforosteogenesisandorganogenesisduringembryonicdevelopment,andalsoplayaroleintissuehealinginadults.NoggininhibitsBMPactivitybybindingtothemwithhighaffinity,blockingtheirABIlitytobindtotheirreceptor.
Description:
HumanNoggin,alsoknownassymphalangism1(SYM1)orsynostoses(multiple)syndrome1(SYNS1),GenBankAccessionNo.NM_005450,a.a.28-232(end),disulfide-linkedhomodimer.MW=~28kDa(monomer).Source:human293cells.EndotoxinLevel:<1 EU/μg. BIOLOGicalActivity:measuredbyNoggin’sabilitytoinhibitBMP-4-inducedalkalinephosphataseproductionbyC2C12mousemyoblastcells.TheED50is
UniProt
Q13253
Synonym(s):
Noggin,symphalangism1,SYM1,synostoses(multiple)syndrome1,SYNS1
EndotoxinLevel:
< 1EU per µg of Noggin as determined by the LAL method.
BiologicalActivity:
MeasuredbyNoggin’sabilitytoinhibitBMP-4-inducedalkalinephosphataseproductionbyC2C12mousemyoblastcells.TheED50is<20 ng/ml in the presence of 30 ng/ml of human BMP-4.
Formulation:
Lyophilizedfroma0.2µmfiltered0.1mg/mlsolutionof50mMTris,pH8.0,1.2MNaCl,2.7mMKCl,0.1%BSA
Format:
Lyophilizedsolid
Reconstitution:
Reconstituteinsterilewaterwith0.1%BSAtoafinalconcentrationof0.1mg/ml.Finalformulationwillbe50mMTris,pH8.0,1.2MNaCl,2.7mMKCl,0.1%BSA.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/Stability:

≥12months(lyophilized)at-20°C.Storereconstitutedproteininaliquotsat-20°Cto–70°Cforupto6months.Avoidfreeze/thawcycles.

Application(s):
Usefulforcellcultureandforthestudyofsignalinganddevelopmentalpathways.Alsousefulforreceptorbindingstudies,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Tao,Y.X.,etal.(2010).IndianJ.Exp.Biol.48(5):444-52.
2.Mfopou,J.K.,etal.(2010).Gastroenterology.138(7):2233-2245.
3.Chaturvedi,G.,etal.(2009).CellProlif.42(4):425-33
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。