Bpsbioscience/小鼠白细胞介素-2/90185-A/5µg
商品编号：
90185-A
品牌：
bpsbioscience
市场价：
¥2600.00
美元价：
1560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Mouse
HostSpecies:E.coli
MW:15kDa
Genbank#:P04351
a.a:22–169
Background:
IL-2isproducedmainlybyT-cellsexpressingthesurfaceantigenCD4followingcellactivationbymitogensorallogen.Interleukin-2(IL-2)hasmultiple,sometimesopposing,functionsduringaninflammatoryresponse.ItisapotentinducerofT-cellproliferationandT-helper1(Th1)andTh2effectorT-celldifferentiationandprovidesTcellswithalong-lastingcompetitiveadvantageresultingintheoptimalsurvivalandfunctionofmemorycells.Inaregulatoryrole,IL-2isimportantforthedevelopment,survival,andfunctionofregulatoryTcells,itenhancesFas-mediatedactivation-inducedcelldeath,anditinhibitsthedevelopmentofinflammatoryTh17cells.Thus,initsdualandcontrastingfunctions,IL-2contributestoboththeinductionandtheterminationofinflammatoryimmuneresponses.
Description:
RecombinantIL-2isadisulfide-linkedmonomericproteinconsistingof150aminoacidresidues,andmigratesasanapproximately17kDaproteinundernon-reducingandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingmurineInterleukin-2maturechainwasexpressedinE.coli.
UniProt
P04351
Synonym(s):
IL-2,Lymphokine,TCGF,TCellGrowthFactor,Aldesleukin,Interleukin-2,IL2
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
TheED50wasdeterminedbythedosedependentstimulationofmurineCTLL-2cellsis<0.1ng/ml,correspondingtoaspecificactivityof>1.0x107units/mg.
Formulation:
Lyophilizedfrom0.2µmfilteredPBS,pH7.0.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.ShevachEM.TrendsImmunol.2012Dec,33(12):626-32.
2.DoomsH,AbbasAK.EurJImmunol.2010Jun,40(6):1538-40.
2.DoomsH,AbbasAK.EurJImmunol.2010Jun,40(6):1538-40.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
PTSSSTSSSTAEAQQQQQQQQQQQQHLEQLLMDLQELLSRMENYRNLKLPRMLTFKFYLPKQATELKDLQCLEDELGPLRHVLDLTQSKSFQLEDAENFISNIRVTVVKLKGSDNTFECQFDDESATVVDFLRRWIAFCQSIISTSPQ
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
