Bpsbioscience/UNC0224/27303/10 mg
商品编号：
27303
品牌：
bpsbioscience
市场价：
¥5400.00
美元价：
3240.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 485.7 kDa
CAS Registry #: 1197196-48-7
Formula: C26H43N7O2
Description:
UNC0224 is a potent and selective inhibitor of G9a, a histone methyltransferase (HMT). It also inhibits GLP, a closely-related H3K9 HMT, but is more than 1,000-fold selective against SET7/9 and SET8.
Purity:
≥98% by HPLC
Biological Activity:
UNC0224 inhibits G9a with an IC50 value of 15 nM. It has been shown to inhibit GLP with assay-dependent IC50 values of 20-58 nM.
Solubility:
Soluble in DMSO, DMF and ethanol, purged with an inert gas. Solubility in DMSO and DMF is approximately 2 mg/ml, and solubility in ethanol is ~15 mg/ml.
Format:
A crystalline solid.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Tachibana, M., et al., Genes Dev. 2002; 16:1779-1791.
2. Wagschal, A., et al., Mol. Cell. Biol. 2008; 28(3):1104-1113.
3. Thomas, L.R., et al., J. Immunol. 2008; 181:485-493.
2. Wagschal, A., et al., Mol. Cell. Biol. 2008; 28(3):1104-1113.
3. Thomas, L.R., et al., J. Immunol. 2008; 181:485-493.
Scientific Category:
Methyltransferase
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
