Bpsbioscience/PRMT5 TR-FRET Assay Kit/52171/384 reactions-免疫在线蚂蚁淘旗下平台

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商品详细Bpsbioscience/PRMT5 TR-FRET Assay Kit/52171/384 reactions

Bpsbioscience/PRMT5 TR-FRET Assay Kit/52171/384 reactions

商品编号： 52171

品牌： bpsbioscience

市场价： ¥21600.00

美元价： 12960.00

产地：美国(厂家直采)

公司：

产品分类：其它检测试剂盒

公司分类： Other_kits

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商品介绍

Background:

PRMT5isahistonemethyltransferasethatexhibitsmethylationactivitytowardH4-R3.PRMT5isacriticalregulatory-proteinlinkedtogenomeorganization,cellcycleregulation,andstemcelldifferentiation.PRMT5transfersmethylgroupsfromS-adenosylmethoinine(SAM)toformmonoandsymmetricdi-methylatedarginineresiduesinhistoneproteins,transcriptionfactors,andotherregulatoryproteins.Givenitsregulatoryfunction,PRMT5isbelievedtocontributetotumOrigenesis.Itsdysregulatedactivityhasbeenassociatedwithmanycancersincludinglymphomas,lung,andbreastcancer.Additionally,PRMT5hasbeenlinkedtootherdiseasesincludingkidneyandheartdiseaseaswellasneurologicaldisorderssuchasHuntington’sandAlzheimer’sdiseases.

Description:

ThePRMT5TR-FRETAssayKitisdesignedtomeasurePRMT5activityinahomogeneous384reactionformat.PRMT5isahistonemethyltransferasethatexhibitsmethylationactivitytowardH4-R3.ThisFRET-basedassayrequiresnotime-consumingwashingsteps,makingitespeciallysuitableforhighthroughputscreeningapplications.ThekeytothePRMT5TR-FRETAssayKitisahighlyspecificantibodythatrecognizesmethylatedsubstrate.

Synonym(s):

PRMT5,HRMT1L5,IBP72,JBP1,SKB1

SuppliedAs:

ThePRMT5TR-FRETAssayKitcomesinaconvenientformat,withhistoneH4peptidesubstrate,aEu-labeledantibody,S-adenosylmethionine,methyltransferaseassaybuffer,FRETdetectionbuffer,dye-labeledacceptor,andpurifiedPRMT5.

Format:

COMPONENTS:

Instructionsforuse:

Seeassaykitdatasheetfordetailedprotocol.

Storage/StABIlity:

12monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.

Application(s):

GreatforstudyingenzymekineticsandHTSapplications.

Reference(s):

Yang,Y.,Bedford,M.T.2013.NatRevCancer.13(1):37-50.

Warning(s):

Avoidfreeze/thawcycles.

ScientificCategory:

Methyltransferase

ProductType:

AssayKit

Datashownislot-specific.Contactusforspecificinformationonotherlots.

品牌介绍

bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。

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