Bpsbioscience/人/小鼠ERK2（K52R），非活性，His标签/40056/100µg
商品编号：
40056
品牌：
bpsbioscience
市场价：
¥7400.00
美元价：
4440.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Mouse
Host Species: E. coli
MW: 42 kDa
Genbank #: NM_0011949
Tag(s): N-terminal His-tag
a.a: full length
Description:
Human/Mouse ERK2/MAPK2 (K52R) (GenBank Accession No. NM_0011949), full length with mutation on lysine52 to arginine and with an N-terminal His-tag, MW=42 kDa, expressed in E. coli . The K52R mutation prevents ATP binding, making the kinase inactive.
Synonym(s):
ERK2, MAPK1, mitogen-activated protein kinase 1, Extracellular Signal-Regulated Kinase 2, PRKM
Specific Activity:
inactive
Formulation:
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 125 mM imidazole, 3 mM DTT, 10% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at -80°C.
Application(s):
Useful as a substrate for MEK1.
Reference(s):
1. Robinson, M.J., et al. Biochemistry. 1996 May 7;35(18):5641-6.
2. Mitsushima, M. et al. Cell Res. 313 (9), 1830- 1838 (2007).
3. Wille, L. et al. Mol. Immunol. 44 (12), 3085- 3091 (2007).
Application Reference(s):
1. BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity (2017)
Notes:
The human and mouse versions of this protein share 100% amino acid homology.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Substrate
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
