Bpsbioscience/PP242/27063/10毫克
商品编号：
27063
品牌：
bpsbioscience
市场价：
¥2300.00
美元价：
1380.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:308.3Da
CASRegistry#:1092351-67-1
Formula:C16H16N6O
Description:
PP242isaninhibitoratthekinasedomainofthemammaliantargetofrapamycin(mTOR),whichisaSer/Thrkinaseandacellgrowthcontroller.PP242inhibitsmTORC1moreeffectivelythanrapamycin.Unlikerapamycin,PP242inhibitsbothmTORC1andmTORC2withIC50valuesof0.03and0.058µM,respectivelyanditcaninhibitcap-dependenttranslation.PP242functionsbyblockingthephosphorylationofAktatS473andpreventingmTORactivation.PP242exhitibitsIC50valuesforotherkinasesof0.11µM(JAK2),0.41µM(DNAPK),0.05µM(PKC?),0.2µM(PKCβIandII),4.4µM(EGFR),and1.5µM(VEGFR2).
Synonym(s):
Torkinib
Purity:
≥99%
Solubility:
SolubleinDMSO
Format:
Whitetooff-whitesolid
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
Feldman,M.E.,etal.PLoSBiol.7:371-383(2009).
ScientificCategory:
Kinase
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
