Bpsbioscience/PIK-75/27001/10 mg
商品编号：
27001
品牌：
bpsbioscience
市场价：
¥3300.00
美元价：
1980.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 488.7 Da
CAS Registry #: 372196-77-5
Formula: C16H14BrN5O4S•HCl
Description:
PIK-75 is a preferential inhibitor of the p110α/p120γ forms of phosphatidylinositol 3-kinase (PI3K), which comprise a class of lipid kinases that phosphorylate phosphatidylinositol 4,5-bisphosphate (PIP2) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 activates Akt and mTOR, and plays important roles in cell growth and survival.
Purity:
≥95% by HPLC.
Biological Activity:
PIK-75 Hydrochloride is a hydrochloride salt form of PIK-75, with IC50 of 6 nM, 1300 nM, 76 nM, 510 nM for p110α, p110β, p120γ, p110δ, respectively.
Solubility:
Soluble in DMSO.
Format:
A crystalline solid.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Dagia, N.M., et al. Am. J. Physiol. Cell Physiol. 298: C929-C941 (2010)
2. Kim, J.E., et al. Biochem. Biophys. Res. Commun. 379: 830-834 (2009)
3. Hers, I. Blood 110: 4243-4252 (2007)
2. Kim, J.E., et al. Biochem. Biophys. Res. Commun. 379: 830-834 (2009)
3. Hers, I. Blood 110: 4243-4252 (2007)
Scientific Category:
Kinase
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
