4000-520-616
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4000-520-616
当前位置: 首页 > 产品中心 > Routine_cell_strain > Bpsbioscience/IDO2 Cellular Activity QuickDetect™ Supplements/62001-1/100 reactions
商品详细Bpsbioscience/IDO2 Cellular Activity QuickDetect™ Supplements/62001-1/100 reactions
Bpsbioscience/IDO2 Cellular Activity QuickDetect™ Supplements/62001-1/100 reactions
Bpsbioscience/IDO2 Cellular Activity QuickDetect™ Supplements/62001-1/100 reactions
商品编号: 62001-1
品牌: bpsbioscience
市场价: ¥4300.00
美元价: 2580.00
产地: 美国(厂家直采)
公司:
产品分类: 常规细胞株
公司分类: Routine_cell_strain
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Background:
L-tryptophan(L-Trp)isanessentialaminoacidnecessaryforproteinsynthesisinmammaliancells.TheL-Trptokynurenine(Kyn)pathwayisfirmlyestablishedasakeyregulatorofinnateandadaptiveimmunity.CatabolismofL-TrptoKynmaintainsanimmunosuppressivemicroenvironmentbystarvingimmunecellsofL-Trp.Additionally,thereleaseddegradationproductsofL-Trphaveimmunosuppressivefunctions.Indoleamine2,3-dioxygenases(IDO1&IDO2),twooftheratelimitingenzymesinthispathway,areupregulatedinmanytumorsandprovidecancercellswithanavenueforimmuneevasion.
Description:
TheIDO2CellularActivityQuickDetectTMSupplementsaredesignedtocomplementthehIDO2-HEK293RecombinantCellLine(BPSCat.#60532)orotherIDO2-expressingcelllines.ThiskitcontainsthecellculturemediumsupplementsnecessaryforactivationofIDO2andfortheanalysisanddetectionofIndoleamine2,3dioxygenase2(IDO2)-catalyzedconversionofL-tryptophan(L-Trp)toKynurenine(Kyn).Thesupplementsandthedetectionreagents,whenusedasdescribed,allowforindirectmeasurementofKynlevelsbyanalyzingabsorptionat480nm.
Synonym(s):
Indoleamine2,3-dioxygenase2,IDO2
Format:
Components

Instructionsforuse:
seedatasheetfordetailedculturingandassayprotocol.
Storage/StABIlity:
Stableforatleast6monthswhenstoredasdirected
Application(s):
MonitorIDO2pathwayactivity.ScreenforactivatorsorinhibitorsofIDO2inacellularcontext
Reference(s):
1.Metz,R.,etal.,Int.Immunol.2014;26:357–367.

2.Fatokun,A.,etal.,AminoAcids2013;45:1319-1329.

Notes:

Contactusforpricing.

LicenseDisclosure:Purchaseofthiscelllinegrantsyouwitha10-yearlicensetousethiscelllineinyourimmediatelaboratory,forresearchuseonly.Thislicensedoesnotpermityoutoshare,distribute,sell,sublicense,orotherwisemakethecelllineavailableforusetootherlaboratories,departments,researchinstitutions,hospitals,universities,orbiotechcompanies.Thelicensedoesnotpermituseofthiscelllineinhumansorfortherapeuticordruguse.Thelicensedoesnotpermitmodificationofthecelllineinanyway.InappropriateuseordistributionofthiscelllinewillresultinrevocationofthelicenseandresultinanimmediateceaseofsalesanddistributionofBPSproductstoyourlaboratory.BPSdoesnotwarrantthesuitabilityofthecelllineforanyparticularuse,anddoesnotacceptanyliabilityinconnectionwiththehandlingoruseofthecellline.Modificationsofthiscellline,transfertoanotherfacility,orcommercialuseofthecellsmayrequireaseparatelicenseandadditionalfees;contactsales@bpSBIoscience.comfordetails.PublicationsusingthiscelllineshouldreferenceBPSBioscience,Inc.,SanDiego.

Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Immunotherapy
ProductType:
CellLine
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。