Bpsbioscience/Human Tumor Necrosis Factor-beta/90245-A/5 µg
商品编号：
90245-A
品牌：
bpsbioscience
市场价：
¥2600.00
美元价：
1560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:21kDa
Genbank#:P01374
a.a:35–205
Background:
TNF-βisapotentmediatorofinflammatoryandimmuneresponses.ItbelongstotheTNFfamilyofligandsandsignalsthroughTNFR1andTNFR2.TNF-βisproducedbyactivatedTandBlymphocytes,andhassimilaractivitiestoTNF-alpha.LikeTNF-α,TNF-βisinvolvedintheregulationofvariousBIOLOGicalprocessesincludingcellproliferation,differentiation,apoptosis,lipidmetabolism,coagulation,andneurotransmission.TNF-βissecretedasasolublepolypeptide,butcanformheterotrimerswithlymphotoxin-β,whicheffectivelyanchorstheTNF-βtothecellsurface.TNF-βiscytotoxictoawiderangeoftumorcells.
Description:
RecombinantTNF-betaisanondisulfide-linkedhomotrimerprotein,eachconsistingof172aminoacidsandmigratesasanapproximately21kDaproteinunderreducingconditions.OptimizedDNAsequenceencodingHumanTumorNecrosisFactor-betachainwasexpressedinE.coli.
UniProt
P01375
Synonym(s):
TNF-betaTNFb,TumorNecrosisFactor-beta,LymphotoxinAlpha,LT-alpha
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BiologicalActivity:
TheED50wasmeasuredinacytotoxicityassayusingmouseL929cellsinthepresenceofthemetabolicinhibitoractinomycin,andwasdeterminedtobelessthan0.1ng/ml.
Formulation:
Lyophilizedfroma0.2µmfilteredPBSsolution,pH7.5.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.Ishibashi,K.,etal.LeukLymphoma.1992Aug,7(5-6):409-17.
2.TraceyKJ,CeramiA.AnnuRevMed.1994,45:491-503
3.SedgwickJD,etal.ImmunolToday.2000Mar,21(3):110-3.
2.TraceyKJ,CeramiA.AnnuRevMed.1994,45:491-503
3.SedgwickJD,etal.ImmunolToday.2000Mar,21(3):110-3.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
LPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
