Bpsbioscience/人胸腺基质淋巴细胞生成素/90250-B/10µg
商品编号:
90250-B
品牌:
bpsbioscience
市场价:
¥4100.00
美元价:
2460.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:15kDa
Genbank#:Q969D9
a.a:29–159
Background:
Thymicstromallymphopoietin(TSLP)promotesthegrowthandactivationofBcells.Italsohaswide-rangingimpactsonbothhematopoieticandnonhematopoieticcelllineages,includingdendriticcells,basophils,eosinophils,mastcells,CD4?,CD8?andnaturalkillerTcells,andepithelialcells.TSLPplaysaroleinthepromotionofTH2responsesinlung-andskin-specificallergicdisorders,anditalsoisinvolvedintheblockadeofTH1/TH17responsesandthepromotionofcancerandautoimmunity.
Description:
RecombinantTSLPisadisulfide-linkedmonomericproteinconsistingof132aminoacidresidues,andmigratesasanapproximately15kDaproteinundernon-reducingconditionsandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanTSLPmaturechainwasexpressedinE.coli.
UniProt
Q969D9
Synonym(s):
TSLP,Thymicstromallymphopoietin
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
TheED50wasdeterminedbythedose-dependentproliferationofhumanIL-7RαandhumanTSLPRco-transfectedmouseBaF3cellstobe<3.0ng/ml.
Formulation:
Lyophilizedfroma0.2µmfiltered1mg/mlsolutionof20mMphosphatebuffer,pH7.4,150mMNaCl.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.ZieglerSF,etal.AdvPharmacol.2013,66:129-55.
2.YuX,etal.CellImmunol.2012Oct,279(2):174-9.
3.RoanF,etal.JLeukocBiol.2012Jun,91(6):877-86.
2.YuX,etal.CellImmunol.2012Oct,279(2):174-9.
3.RoanF,etal.JLeukocBiol.2012Jun,91(6):877-86.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
YDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。