Bpsbioscience/人血小板生成素/90249-A/2µg
商品编号：
90249-A
品牌：
bpsbioscience
市场价：
¥2600.00
美元价：
1560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:80kDa
Genbank#:P40225
a.a:22–353
Background:
Thrombopoietin(TPO),knownalsoasTSF(thrombopoiesisstimulatingfactor),formediatorsubstancesthatfunctionasnaturalstimulatorsofmegakaryocytopoiesisandthus,promotethedifferentiationofplatelets.TPOstimulatesanincreaseinthesizesandnumbersofmegakaryocytes.Italsoincreasesthenumberofsmallacetyl-cholinesterasepositivecellsthatareearlyprecursorcellsofthemegakaryocyticlineage.TPOisaproteinof332aminoacidsthatshowssignificanthomologywithEpo(erythropoietin)initsN-terminaldomain.AcomparisonofhumanandporcineTPOsequencesshows83%identitybetweentheerythropoietin-likedomainsbutonly67%betweentheC-terminaldomains.
Description:
RecombinantTPOisdisulfide-linkedmonomerproteinconsistingof332aminoacidresidues,andmigratesduetoglycosylationasanapproximately80kDaproteinundernon-reducingconditionsandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanTPOerythropoeitindomainwasexpressedinChineseHamsterOvarycells.
UniProt
P07202
Synonym(s):
TPO,Thrombopoietin,MGDF,MegakaryocyteGrowthAndDevelopmentFactor,MKCSF,TSF,thrombopoiesisstimulatingfactor
Purity:
≥98%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
TheED50wasdeterminedbythedose-dependentproliferationofMo7ecellstobeintherangeof1.0-2.0ng/ml.
Formulation:
Lyophilizedfroma0.2µmfilteredPBSsolution,pH7.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.LupiaE,etal.MediatorsInflamm.2012,2012:390892.
2.BascianoPA,BusselJB.CurrOpinHematol.2012Sep,19(5):392-8.
3.deGraafCA,MetcalfD.CellCycle.2011May15,10(10):1582-9.
2.BascianoPA,BusselJB.CurrOpinHematol.2012Sep,19(5):392-8.
3.deGraafCA,MetcalfD.CellCycle.2011May15,10(10):1582-9.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
SPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
