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Bpsbioscience/Human Stromal Cell-Derived Factor-1 alpha/90237-B/10 µg
Bpsbioscience/Human Stromal Cell-Derived Factor-1 alpha/90237-B/10 µg
商品编号：
90237-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
产品分类：
常规细胞株
公司分类：
Routine_cell_strain
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:8kDa
Genbank#:P48061
a.a:22–89
Background:
SDF-1alphaandSDF-1betaaresmallcytokinesbelongingtotheCXC-Chemokines.SDF-1isidenticalwithachemokinereportedtofunctionasapre-B-cellgrowthfactorinthepresenceofIL-7andisolatedoriginallyfromamurinebonemarrowstromalcellline.HumanSDF-1alphaandSDF-1betaareencodedbyasinglegeneandarisebyalternativesplicing.SDF-1actsonlymphocytesandmonocytesbutnotneutrophilsinvitroandisahighlypotentchemoattractantformononuclearcellsinvivo.Inaddition,SDF-1alsoinducesintracellularactinpolymerizationinlymphocytes.SDFactsasachemoattractantforhumanhematopoieticProgenitorcellsexpressingCD34givingrisetomixedtypesofprogenitors,andmoreprimitivetypes.Thechemotacticresponseisinhibitedbypertussistoxin.ChemotaxisofCD34(+)cellsinresponsetoSDFisincreasedbyIL-3invitro.SDFhasbeenshownalsotoinduceatransientelevationofcytoplasmiccalciuminthesecells.
Description:
RecombinantSDF-1alphaisadisulfide-linkedmonomerproteinconsistingof69aminoacidresidues,migratesasanapproximately8kDaproteinundernon-reducingandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodinghumanStromalCell-DerivedFactor-1alphawasexpressedinE.coli.
UniProt
P48061
Synonym(s):
StromalCell-DerivedFactor-1alpha,SDF1a,CXCL12,TLSF-A,
Purity:
≥97%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
Formulation:
Lyophilizedfroma0.2µmfilteredconcentrated(1mg/ml)solutionin20mMphosphatebuffer,pH7.2.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/Stability:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.HiesingerW,etal.TrendsCardiovascMed.2012Aug,22(6):139-44.
2.FelixAS,etal.CancerMicroenviron.2010Feb26,3(1):49-56.
2.FelixAS,etal.CancerMicroenviron.2010Feb26,3(1):49-56.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
