Bpsbioscience/Zaprinast/27218/10 mg
商品编号：
27218
品牌：
bpsbioscience
市场价：
¥2200.00
美元价：
1320.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:271.3Da
CASRegistry#:37762-06-4
Formula:C13H13N5O2
Description:
ZaprinastisacGMP-specificPDEinhibitorwhichmoderatelyinhibitsPDE5andPDE6.ItweaklyinhibitsPDE9,PDE10andPDE11.Sildenafil(Viagra™)wasdevelopedfromZaprinast,whichenhancesthevasodilatoryeffectsofnitricoxideinarangeofvasculartissuesbyprolongingthecGMP-mediatedactivationofcGMP-dependentproteinkinase.Also,GPR35isactivatedbyZaprinast.
Purity:
≥98%byHPLC
BIOLOGicalActivity:
ZaprinastinhibitsPDE5andPDE6withIC50valuesof0.5-0.76µMand0.15µM,respectively.
Solubility:
SolubleinDMSOandDMF,purgedwithaninertgas.SolubilityinDMSOandDMFis~10mg/ml.Formaximumsolubility,dissolveinDMFandthendilutewiththeaqueousbufferofchoice.
Format:
Acrystallinesolid.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Nakamizo,T.,etal.,J.Neurosci.Res.2003;71:485-495.
2.Gibson,A.,etal.,Eur.J.Pharmacol.2001;411:1-10.
3.Taniguchi,Y.,etal.,FEBSLett.2006;580:5003-5008.
2.Gibson,A.,etal.,Eur.J.Pharmacol.2001;411:1-10.
3.Taniguchi,Y.,etal.,FEBSLett.2006;580:5003-5008.
ScientificCategory:
PDE
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
