Bpsbioscience/盐酸伐地那非三水合物/27776-1/100 mg
商品编号：
27776-1
品牌：
bpsbioscience
市场价：
¥9200.00
美元价：
5520.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:579.1Da
CASRegistry#:224785-90-4
Formula:C23H32N6O4S•HCl•3>H2O
Target:PDE5
Background:
Vardenafilisfrequentlyusedinthetreatmenterectiledysfunction,andistheactiveingredientinLevitra.IthasbeenreportedtosignificantlyenhancetheSNP-induced,ACh-inducedandtransmuralelectricalstimulation-inducedrelaxationofhumantrabecularsmoothmuscle.VardenafilhasbeenrevealedtoincreasetheamountofcGMPinhumancorpuscavernosum.
Description:
Vardenafilisapotentandselectiveinhibitorofphosphodiesterasetype5(PDE5)withtheIC50valueof0.7nMinenzymaticassayinvitro.
Synonym(s):
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-onemonohydrochloridetrihydrate
BIOLOGicalActivity:
VardenafilhasshownagreaterselectiveinhibitiontowardsPDE5(IC50=0.7nM)vs.PDEsfrombovine,withtheIC50valuesof180nM,>10µM,2.5µM,4µMand11nMforPDE1,PDE2,PDE3,PDE4andPDE6,respectively.ItisshowsselectivityforPDE5vs.over300-foldrelativetoPDE11andover1000-foldrelativetoPDEs8,9,and10.
Solubility:
Solubleinethanolor0.1MHCl.Onlyslightlysolubleinwater.
Format:
nearlycolourlesssolid
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
SaenzdeTejadaI.,etal.IntJImpotRes.2001Oct;13(5):282-90.
ScientificCategory:
PDEInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
