Bpsbioscience/Histone Octamer (full length), His-tag/52037/100 μg
商品编号：
52037
品牌：
bpsbioscience
市场价：
¥9300.00
美元价：
5580.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 116 kDa
Genbank #: NM_033445, NM_003528, NM_003532, NM_003548
Tag(s): N-terminal His-tag
Background:
The histone octamer is composed of a central heterotetramer of two copies of both histones H3 and H4, flanked by two heterodimers of histones H2A and H2B. The octamer assembles when the H3/H4 tetramer complexes with two H2A/H2B dimers. These histones of the histone octamer all contain N-terminal tails that emanate from their central histone folds and are targets for epigenetic modification.
Description:
Human recombinant histone octamer consisting of 2 molecules each of histones H2A (a.a. 2-130(end)), H2B (a.a. 2-126(end)), H3 (a.a. 2-137(end)), and H4 (a.a. 2-103(end)), expressed in an E. coli expression system. GenBank Accession Nos. are NM_033445, NM_003528, NM_003532, and NM_003548, respectively. Each histone protein has an N-terminal His-tag. Global MW = 113.8 kDa.
UniProt
Q7L7L0, Q16778, P68431, P62805
Formulation:
10 mM Tris pH 7.4, 2 M NaCl, 1 mM EDTA, 5 mM BME, and 10% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
Stable at -80°C for at least 6 months from date of receipt, when stored as directed
Application(s):
Substrate for histone methyltransferase or acetyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases and acetyltransferases for drug discovery and HTS applications. Since the recombinant histone proteins in thi
Reference(s):
1. Miller KM, Jackson SP. Biochem Soc Trans 40(2):370-6 (2012).
2. Raut VV, Pandey SM, Sainis JK. Ann Bot 108(7):1235-46 (2011).
3. Park K, Fasman GD. Biochemistry. 1987 Dec 15;26(25):8042-5.
4. Meagher, R.B., Mussar, K.J., Epigenetics Chromatin 2012 Jul 20,5(1):11.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Methyltransferase
Product Type:
Substrate
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
