Bpsbioscience/EPHA6, GST-tag/40194/10 µg
商品编号：
40194
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: Sf9 insect cells
MW: 73 kDa
Genbank #: NM_001080448
Tag(s): N-terminal GST-tag
a.a: 561–end
Background:
EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia (1). Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context (2).
Description:
Recombinant human EPHA6 (a.a. 561-end), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Synonym(s):
EPA6, FLJ35246, PRO57066, DKFZp434C1418, Ephrin Type A Receptor 6
Purity:
≥70%
Formulation:
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at -80°C.
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Shaut C A, et al: HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia. Dev Dyn. 2007 Apr;236(4):951-60.
2. Savelieva K V, et al: Learning and memory impairment in Eph receptor A6 knockout mice. Neurosci Lett. 2008 Jun 20;438(2):205-9.
2. Savelieva K V, et al: Learning and memory impairment in Eph receptor A6 knockout mice. Neurosci Lett. 2008 Jun 20;438(2):205-9.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Receptor Tyrosine
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
