Bpsbioscience/EGFR, GST-tag/40187/10 µg
商品编号：
40187
品牌：
bpsbioscience
市场价：
¥7100.00
美元价：
4260.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:87.3kDa
Genbank#:NM_005228
Tag(s):N-terminalGST-tag
a.a:668–1210
Description:
HumanEGFR(GenBankAccessionNo.NM_005228),a.a.668-1210withN-terminalGST-tag,MW=87.3kDa,expressedinaBaculovirusinfectedSf9cellexpressionsystem.
Synonym(s):
EGFR,EpidermalGrowthFactorReceptor,ERBB,ErbB-1,HER1,MENA
SpecificActivity:
≥800pmol/min/μg.
AssayConditions:
Assaywasperformedinakinasebuffercontaining0.2mMDTTusingPoly-(Glu4:Tyr)-biotinsubstrate(0.2mg/ml)and20μMATP.Reactionwasdoneat30°Cfor30min.ATPtransferredwascalculatedusingKinase-Gloreagent(Promega).
Formulation:
50mMTris-HCl,pH8.0,150mMNaCl,10%glyceroland1mMDTT.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat–80°C
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Nakamura,J.L.ExpertOpin.Ther.Targets11(4),463-472(2007).
2.Kim,H.J.,etal.Curr.Biol.17(5),455-461(2007).
ApplicationReference(s):
1.Synthesis,characterizationandBIOLOGicalevaluationofformononetinderivativesasnovelEGFRinhibitorsviainhibitinggrowth,migrationandinducingapoptosisinbreastcancercellline (2017)
2. FirstBispecificInhibitorsoftheEpidermalGrowthFactorReceptorKinaseandtheNF-κBActivityAsNovelAnticancerAgents(2017)
3. Design,synthesisandinvitroanti-proliferativeactivityof4,6-quinazolinediaminesaspotentEGFR-TKinhibitors(2013)
4. CytotoxicepipolythiodioxopiperazinealkaloidsfromfilamentousfungioftheBionectriaceae (2012)
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/ReceptorTyrosine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
