Bpsbioscience/CD73, Avi-His-Tag (Mouse)/72523/100 μg
商品编号：
72523
品牌：
bpsbioscience
市场价：
¥6500.00
美元价：
3900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Mouse
HostSpecies:HEK293
MW:61kDa
Tag(s):Avi-His-Tag
a.a:29-549
Background:
CD39contributestoimmuneregulationthroughthehydrolysisofATPtoAMPintheratelimitingstepofextracellularadenosineproduction.CD39isexpressedonthesurfaceofmultiplecellsoftheimmunesystemincludingT-cells,Naturalkillercells,B-cells,dendriticcellsandmacrophages.Inaddition,highlevelsofCD39expressionhavebeenassociatedwiththetumormicroenvironment(TME).ResearchaimedatreducingimmunosuppressionbyCD39activityhasresultedinthestudyofasmallmoleculeinhibitor,POM1,andmultipleanti-CD39antibodiesselectedforblockingenzymaticactivity ordecreasingCD39expression.
Description:
MouseCD73,alsoknownas5"-nucleotidaseandEcto-5"-nucleotidase,GenBankAccessionNo.NM_011851,a.a.29-549withC-terminalAvi-His-tag,expressedinaHEK293cellexpressionsystem.MW=61kDa.ThisproteinrunsatahigherMWbySDS-PAGEduetoglycosylation.
UniProt
Q61503
Synonym(s):
NT5E,PPARG,ADIPOQ,5"-NucleotidaseEcto,PeroxisomeProliferatorActivatedReceptorGamma,Adiponectin,C1QAndCollagenDomainContaining,ENTPD1,Ecto-5"-nucleotidase
Formulation:
8mMPhosphate,pH7.4,110mMNaCl,2.2mMKCl,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
Atleast6monthsat-80°C
Application(s):
Usefulforstudyingenzymekinetics,substratespecificity,andscreeninginhibitors.
Reference(s):
1.Deaglio,S.etal.,J.Exp.Med.2007;204(6):1257-1265.2.Thompson,L.F.,etal.,J.Exp.Med.2004;200(11):1395-1405.
Notes:
Theaggregationstateofthisproducthasbeenconfirmedtobe<10%
Warning(s):
Avoidfreeze/thawcycles.Storingdilutedproteinisnotrecommended,ifnecessary,usecarrierprotein(BSA0.1–0.5%).
ScientificCategory:
Immunotherapy
ProductType:
Protein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
