Bpsbioscience/Valproic Acid/27207/10 g
商品编号：
27207
品牌：
bpsbioscience
市场价：
¥2300.00
美元价：
1380.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 167.2 Da
CAS Registry #: 1069-66-5
Formula: C8H16O2 Na
Description:
Valproic acid inhibits histone deacetylases (HDACs), in particular Class I HDACs. It is an analog of the natural fatty acid valeric acid. Valproic acid also inhibits GSK3 and depletes cellular inositol-1,4,5-triphosphate. It can have strong effects on stem cell differentiation and self-renewal, and it shows promise in treating cancer and Alzheimer’s disease.
Purity:
≥95% by HPLC
Biological Activity:
Valproic acid inhibits Class I HDACs with an IC50 of ~ 2 mM.
Solubility:
Soluble in ethanol, DMSO and dimethyl formamide (DMF). Solubility in ethanol is 30 mg/ml and 5 mg/ml in DMSO and DMF. For organic solvent-free aqueous solutions, prepare by directly dissolving the crystalline compound in aqueous buffers.
Format:
A crystalline solid.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Jung, G., et al., BMC Cell Biol. 2008; 9(66).
2. Bug, G., et al., Cancer Res. 2005; 65(7): 2537 – 2541.
3. Gottlicher, M., et al., EMBO J. 2001; 20(24): 6969 – 6978.
2. Bug, G., et al., Cancer Res. 2005; 65(7): 2537 – 2541.
3. Gottlicher, M., et al., EMBO J. 2001; 20(24): 6969 – 6978.
Scientific Category:
HDAC
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
