Bpsbioscience/Tubacin/27662/1毫克
商品编号：
27662
品牌：
bpsbioscience
市场价：
¥3500.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:721.9Da
CASRegistry#:1350555-93-9
Formula:C41H43N3O7S
Target:HDAC6
Description:
Tubacinisahighlypotentandselective,reversIBLe,cell-permeableHDAC6inhibitor.TubacindoesnotinhibitHDAC6histonedeacetylaseactivity;instead,tubacinisspecificforthetubulindeacetylaseactivityofHDAC6.Itreversiblyinhibitsα-tubulindeacetylationinmammaliancellsandincreasesα-tubulinacetylationlevelswithnoeffectonhistoneacetylationorcellcycleprogression.
Synonym(s):
N-[4-[(2R,4R,6S)-4-[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanylmethyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N"-hydroxyoctanediamide
Purity:
≥98%byHPLC
BIOLOGicalActivity:
Tubacinreversiblyinhibitsα-tubulindeacetylationactivityofHDAC6(IC50=4nM)TheIC50forotherHDACsis1000-foldhigher,makingtubacinbothmoreselectiveandmorepotentthanTubastatinA,whichalsoinhibitsHDAC8.
Solubility:
SolubleinDMSO
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Aldana-MasangkayGI,etal.LeukLymphoma.2011Aug;52(8):1544-55.
2.KawadaJ,etal.JBiolChem.2009Jun19;284(25):17102-9.
2.KawadaJ,etal.JBiolChem.2009Jun19;284(25):17102-9.
ScientificCategory:
DeacetylaseInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
