Bpsbioscience/Human MIP4(CCL18)/90221-B/25 µg
商品编号：
90221-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 8 kDa
Genbank #: P55774
a.a: 21–89
Background:
CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38—, mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma.
Description:
Recombinant CCL18 is a disulfide-linked homodimeric protein consisting of 70 amino acid residues and migrates as an approximately 16 kDa protein under non-reducing conditions and 8 kDa under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human MIP-4 mature chain was expressed in E. coli.
UniProt
P55774
Synonym(s):
CCL18, MIP4, MIP-4, PARC, Pulmonary And Activation-Regulated Chemokine, Macrophage Inflammatory Protein 4, DCCK1, AMAC1
Purity:
≥98% by SDS-PAGE and HPLC
Endotoxin Level:
<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Biological Activity:
Determined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0 ng/ml.
Formulation:
Lyophilized from a 0.2 µm filtered 20 mM Phosphate buffer, 100 mM NaCl, pH 7.5.
Format:
lyophilized protein
Reconstitution:
Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability:
The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.
Reference(s):
1. Chest, Feb 2009, 135: 295 - 302.br>2. J. Immunol., Jul 2008, 181: 1215 - 1223.
3. Ann Rheum Dis, Oct 2007, 66: 1334 - 1338.
3. Ann Rheum Dis, Oct 2007, 66: 1334 - 1338.
Warning(s):
Avoid freeze/thaw cycles
Amino Acid Sequence:
AQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA
Scientific Category:
Cytokine/Growth Factors
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
