Bpsbioscience/PD-1:PD-L2 TR-FRET Assay Kit/72012/384 reactions
商品编号：
72012
品牌：
bpsbioscience
市场价：
¥21400.00
美元价：
12840.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
CellsignalingthroughthePD-1receptoruponbindingthePD-L2ligandattenuatesimmuneresponsesandisexploitedbybothtumorsandviruses.
Description:
ThePD-1:PD-L2TR-FRETAssayKitisdesignedtomeasuretheinhibitionofPD-1bindingtoPD-L2inahomogeneous384reactionformat.CellsignalingthroughthePD-1receptoruponbindingthePD-L2ligandattenuatesimmuneresponsesandisexploitedbybothtumorsandviruses.ThisFRET-basedassayrequiresnotime-consumingwashingsteps,makingitespeciallysuitableforhighthroughputscreeningapplications.Theassayprocedureisstraightforwardandsimple;asamplecontainingeuropium-labeled(Eu)PD-1,dye-labeledacceptor,biotin-labeledPD-L2,andaninhibitorisincubatedfortwohours.Then,thefluorescenceintensityismeasuredusingafluorescencereader.
SuppliedAs:
Thiskitcomesinaconvenient384-wellformat,withEuropium-labeledPD-1andbiotin-labeledPD-L2.
Contraindications:
DMSO>1%,strongacidsorbases,ionicdetergents,highsalt.
Format:
Instructionsforuse:
Seeproductdatasheetfordetailedprotocol.
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
GreatforscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.
Reference(s):
1.Molnar,E.,etal.ProcNatlAcadSciUSA.2008;105:10483-10488.
2.Keir,M.E.,etal.Annu.Rev.Immunol.2008;26:677-704.
2.Keir,M.E.,etal.Annu.Rev.Immunol.2008;26:677-704.
Notes:
MATERIALSORINSTRUMENTSREQUIREDBUTNOTSUPPLIED:
FluorescentmicroplatereadercapableofmeasuringTimeResolvedFluorescenceResonanceEnergyTransfer(TR-FRET)
Adjustablemicropipettorandsteriletips
FluorescentmicroplatereadercapableofmeasuringTimeResolvedFluorescenceResonanceEnergyTransfer(TR-FRET)
Adjustablemicropipettorandsteriletips
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Immunotherapy
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
