
BPS溶解/再溶解™ (+)-JQ1/27403/1毫克
商品编号:
27403
品牌:
bpsbioscience
市场价:
¥1700.00
美元价:
1020.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
MW: 457.0 Da
CAS Registry #: 1268524-70-4
Formula: C23H25ClN4O2S
Description:
(+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains.
Synonym(s):
BET inhibitor, Bromodomain inhibitor
Purity:
≥95% by HPLC
Supplied As:
10 mM solution in anhydrous DMSO
Biological Activity:
(+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.
Format:
DMSO solution
Storage / Stability:
Store at –20°C and avoid multiple freeze-thaw cycles to prevent decomposition.
Reference(s):
Filippakopoulos P., et al. Nature. 468(7327):1067-73 (2011).
Application Reference:
1. BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen
(2014)
2. Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
(2014)
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Bromodomain
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。