Bpsbioscience/OX40[生物素化]:OX40L抑制剂筛选分析试剂盒/72045/96反应
商品编号:
72045
品牌:
bpsbioscience
市场价:
¥21400.00
美元价:
12840.00
产品分类:
其它检测试剂盒
公司分类:
Other_kits
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Background:
OX40(CD134)isaco-stimulatoryreceptorexpressedonthesurfaceofTcells.BindingofOX40toitsligand,OX40L(CD252),presentondendriticcells,potentiatesTcellactivationandTcelleffectorfunction.StudieshaveshownthatOX40agoNISTscanincreaseanti-tumorimmunityandimprovetumor-freesurvivalinpre-clinicalstudies.Alternatively,OX40antagonistsofferpotentialastherapeuticsforinflammatorydiseases.
Description:
TheOX40[Biotinylated]:OX40LInhibitorScreeningAssayKitisdesignedforscreeningandprofilinginhibitorsofOX40:OX40Linteraction.ThekeytothiskitisthehighsensitivityofdetectionofbiotinlabeledOX40bystreptavidin-HRP.Onlyafewsimplestepsonamicrotiterplatearerequiredfortheassay.First,OX40Liscoatedona96-wellplate.Next,OX40-biotinisincubatedwithOX40Lontheplate.Finally,theplateistreatedwithstreptavidin-HRPfollowedbyadditionofanHRPsubstratetoproducechemiluminescence,whichcanthenbemeasuredusingachemiluminescencereader.
Synonym(s):
TumorNecrosisFactorReceptorSuperfamilyMember4,TNFRSF4,CD134,tumornecrosisfactorligandsuperfamilymember4,TNFSF4,CD252
SuppliedAs:
Thiskitcomesinaconvenient96-wellformat,withbiotin-labeledOX40,purifiedOX40L,streptavidin-labeledHRP,andassaybufferfor100bindingreactions.
Format:
COMPONENTS:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
ThiskitisusefulforscreeningforinhibitorsofOX40bindingtoOX40L.
Reference(s):
1.Peng,K.,etal.2014;AAPSJ.16(4):625–633.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Immunotherapy
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。