4000-520-616
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当前位置: 首页 > 产品中心 > Routine_cell_strain > Bpsbioscience/GITR/NF-κB荧光素酶报告基因(Luc)-Jurkat细胞系/60546/2小瓶
商品详细Bpsbioscience/GITR/NF-κB荧光素酶报告基因(Luc)-Jurkat细胞系/60546/2小瓶
Bpsbioscience/GITR/NF-κB荧光素酶报告基因(Luc)-Jurkat细胞系/60546/2小瓶
Bpsbioscience/GITR/NF-κB荧光素酶报告基因(Luc)-Jurkat细胞系/60546/2小瓶
商品编号: 60546
品牌: bpsbioscience
市场价: ¥176000.00
美元价: 105600.00
产地: 美国(厂家直采)
公司:
产品分类: 常规细胞株
公司分类: Routine_cell_strain
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Background:
Glucocorticoid-inducedTNFR-relatedprotein(GITR)isamemberoftheTNFRsuperfamily,expressedinanumberofcellsincludingTcells,naturalkiller(NK)cellsandantigen-presentingcells(APC).GITRL,GITR’snaturalligand,isexpressedmainlybyAPCsandGITR:GITRLinteractionisimportantforactivationoftheimmunesystem.AgoNISTicantibodiestargetingGITRareactivelybeingpursuedaspotentialimmuno-oncologytherapies.
Description:
ThiscelllineexpressesasurfacehumanGITR(glucocorticoid-inducedTNFRfamilyrelatedgene;TNFRSF18;CD357)andanNF-ĸBluciferasereporterconstructthatarestablyintegratedintothegenomeofJurkatT-cells.Thefireflyluciferasegeneiscontrolledby4copiesofNF-kBresponseelementlocatedupstreamoftheTATApromoter.Followingactivationbystimulants,endogenousNF-ĸBtranscriptionfactorsbindtotheDNAresponseelementstoinducetranscriptionoftheluciferasegene.
Synonym(s):
nfkb
HostCellline:
Jurkat
MycoplasmaTesting:
ThiscelllinehasbeenscreenedusingtheMycoAlert™MycoplasmaDetectionKit(Cat.#LT07-118)toconfirmtheabsenceofMycoplasmacontamination.MycoAlertAssayControlSet(Cat.#LT07-518)wasusedasapositivecontrol.
Storage/StABIlity:
Storeinliquidnitrogenimmediatelyuponreceipt.
Application(s):
TheGITRNF-ĸB-luciferase/JurkatcelllineissuitableformonitoringtheactivityofNF-kBsignalinginresponsetoGITRligand(GITRL).
Notes:

Contactusforpricing.

LicenseDisclosure:Purchaseofthiscelllinegrantsyouwitha10-yearlicensetousethiscelllineinyourimmediatelaboratory,forresearchuseonly.Thislicensedoesnotpermityoutoshare,distribute,sell,sublicense,orotherwisemakethecelllineavailableforusetootherlaboratories,departments,researchinstitutions,hospitals,universities,orbiotechcompanies.Thelicensedoesnotpermituseofthiscelllineinhumansorfortherapeuticordruguse.Thelicensedoesnotpermitmodificationofthecelllineinanyway.InappropriateuseordistributionofthiscelllinewillresultinrevocationofthelicenseandresultinanimmediateceaseofsalesanddistributionofBPSproductstoyourlaboratory.BPSdoesnotwarrantthesuitabilityofthecelllineforanyparticularuse,anddoesnotacceptanyliabilityinconnectionwiththehandlingoruseofthecellline.Modificationsofthiscellline,transfertoanotherfacility,orcommercialuseofthecellsmayrequireaseparatelicenseandadditionalfees;contactsales@bpSBIoscience.comfordetails.PublicationsusingthiscelllineshouldreferenceBPSBioscience,Inc.,SanDiego.

ScientificCategory:
Immunotherapy
ProductType:
CellLine
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。