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当前位置: 首页 > 产品中心 > Other_kits > Bpsbioscience/CD73抑制剂筛选分析试剂盒/72055/96反应
商品详细Bpsbioscience/CD73抑制剂筛选分析试剂盒/72055/96反应
Bpsbioscience/CD73抑制剂筛选分析试剂盒/72055/96反应
Bpsbioscience/CD73抑制剂筛选分析试剂盒/72055/96反应
商品编号: 72055
品牌: bpsbioscience
市场价: ¥15800.00
美元价: 9480.00
产地: 美国(厂家直采)
公司:
产品分类: 其它检测试剂盒
公司分类: Other_kits
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Background:

CD39contributestoimmuneregulationthroughthehydrolysisofATPtoAMPintheratelimitingstepofextracellularadenosineproduction.CD39isexpressedonthesurfaceofmultiplecellsoftheimmunesystemincludingT-cells,Naturalkillercells,B-cells,dendriticcellsandmacrophages.Inaddition,highlevelsofCD39expressionhavebeenassociatedwiththetumormicroenvironment(TME).ResearchaimedatreducingimmunosuppressionbyCD39activityhasresultedinthestudyofasmallmoleculeinhibitor,POM1,andmultipleanti-CD39antibodiesselectedforblockingenzymaticactivity ordecreasingCD39expression. 

Description:
TheCD73InhibitorScreeningAssayKitisdesignedtomeasureCD73activityforscreeningandprofilingapplications.TheCD73assaykitcomesinaconvenient96-wellformat,withpurifiedrecombinantCD73enzyme,AMP,CD73assaybuffer,andColorimetricdetectionreagentfor100enzymereactions.
Synonym(s):
5"-nucleotidase,Ecto-5"-nucleotidase
Format:

COMPONENTS:

Instructionsforuse:
Seeproductdatasheetfordetailedassayprotocol.
Storage/StABIlity:
Upto6monthsfromdateofreceipt,whenstoredasrecommended.
Application(s):
GreatforstudyingenzymekineticsandscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.
Reference(s):

Antonioli,L.,etal.,TrendsinCancer,Vol.2,No.2,95-109.

ApplicationReference(s):
1. Membraneparticlesgeneratedfrommesenchymalstromalcellsmodulateimmuneresponsesbyselectivetargetingofpro-inflammatorymonocytes(2017)

Notes:
MATERIALSORINSTRUMENTSREQUIREDBUTNOTSUPPLIED:
UV/VisspectrophotometermicroplatereadercapableofreADIngabsorbanceat630nm
Adjustablemicropipettorandsteriletips
37°Cincubator
Rotatingorrockerplatform
Aluminumfoil
Warning(s):
*ColorimetricdetectionreagentisusedtomeasurethefreephosphatefromtheCD73reaction.Anysourceofinorganicphosphatecaninterferewiththeassay.
Avoidfreeze/thawcycles. 
ScientificCategory:
MetabolicEnzyme,Immunotherapy
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。