Bpsbioscience/CD73抑制剂筛选分析试剂盒/72058/384反应-免疫在线蚂蚁淘旗下平台

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商品详细Bpsbioscience/CD73抑制剂筛选分析试剂盒/72058/384反应

Bpsbioscience/CD73抑制剂筛选分析试剂盒/72058/384反应

商品编号： 72058

品牌： bpsbioscience

市场价： ¥22600.00

美元价： 13560.00

产地：美国(厂家直采)

公司：

产品分类：其它检测试剂盒

公司分类： Other_kits

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Background:

CD39contributestoimmuneregulationthroughthehydrolysisofATPtoAMPintheratelimitingstepofextracellularadenosineproduction.CD39isexpressedonthesurfaceofmultiplecellsoftheimmunesystemincludingT-cells,Naturalkillercells,B-cells,dendriticcellsandmacrophages.Inaddition,highlevelsofCD39expressionhavebeenassociatedwiththetumormicroenvironment(TME).ResearchaimedatreducingimmunosuppressionbyCD39activityhasresultedinthestudyofasmallmoleculeinhibitor,POM1,andmultipleanti-CD39antibodiesselectedforblockingenzymaticactivity ordecreasingCD39expression.

Description:

TheCD73InhibitorScreeningAssayKitisdesignedtomeasureCD73activityforscreeningandprofilingapplications.TheCD73assaykitcomesinaconvenient384-wellformat,withpurifiedrecombinantCD73enzyme,AMP,CD73assaybuffer,andColorimetricdetectionreagentfor384enzymereactions.

Synonym(s):

5"-nucleotidase,Ecto-5"-nucleotidase

Format:

COMPONENTS:

Instructionsforuse:

Seeproductdatasheetfordetailedassayprotocol.

Storage/StABIlity:

Upto6monthsfromdateofreceipt,whenstoredasrecommended.

Application(s):

GreatforstudyingenzymekineticsandscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.

Reference(s):

Antonioli,L.,etal.,TrendsinCancer,Vol.2,No.2,95-109.

ApplicationReference(s):
1. Membraneparticlesgeneratedfrommesenchymalstromalcellsmodulateimmuneresponsesbyselectivetargetingofpro-inflammatorymonocytes(2017)

Notes:

MATERIALSORINSTRUMENTSREQUIREDBUTNOTSUPPLIED:
UV/VisspectrophotometermicroplatereadercapableofreADIngabsorbanceat630nm
Adjustablemicropipettorandsteriletips
37°Cincubator
Rotatingorrockerplatform
Aluminumfoil

Warning(s):

*ColorimetricdetectionreagentisusedtomeasurethefreephosphatefromtheCD73reaction.Anysourceofinorganicphosphatecaninterferewiththeassay.
Avoidfreeze/thawcycles.

ScientificCategory:

MetabolicEnzyme,Immunotherapy

ProductType:

AssayKit

Datashownislot-specific.Contactusforspecificinformationonotherlots.

品牌介绍

bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。

公司介绍

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