
Bpsbioscience/SENP6 Core Domain, His-tag/81097/25 µg
商品编号:
81097
品牌:
bpsbioscience
市场价:
¥8200.00
美元价:
4920.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 55 kDa
Tag(s): His-tag
Background:
SENP6 is a SUMO/sentrin specific protease that functions to remove SUMO from conjugated proteins. SENP6 has been shown to deSUMOylate a member of the ligand-activated transcription factores called retinoid X receptor alpha. The transcriptional activity of RXRalpha is regulated by SUMOylation. Researchers have demonstrated that SENP6 has a preference for SUMO2/3 conjugates over SUMO1 conjugates.
Description:
Human SENP6 Core Domain recombinant protein, with His-tag, expressed in E. coli.
UniProt
Q9GZR1
Synonym(s):
FKSG6, FLJ11355, FLJ11887, KIAA0389, KIAA0797, Sentrin/SUMO-specific protease SENP6, Sentrin-specific protease 6, SSP1, SUMO-1-specific protease 1, SUSP1
Format:
Aqueous buffer solution
Storage / Stability:
Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C.
Application(s):
This enzyme is active in the SUMO3-CHOP assay.
Reference(s):
1. Choi, S.J. et al. Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. J. Biol. Chem. 2006. 281(41):30669-77.
2. Mukhopadhyay D. et al. SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J. Cell Biol. 2006 Sep 25;174(7):939-49.
2. Mukhopadhyay D. et al. SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J. Cell Biol. 2006 Sep 25;174(7):939-49.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Ubiquitination (SUMOylation)
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
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