Bpsbioscience/PLPro, His-tag/81091/25 µg
商品编号:
81091
品牌:
bpsbioscience
市场价:
¥8200.00
美元价:
4920.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species: SARS Coronavirus
Host Species: E. coli
MW: 35 kDa
Tag(s): His-tag
Background:
To date, five human coronaviruses (CoV) have been identified including severe acute respiratory syndrome (SARS).The SARS epidemic of 2002/ 2003 spread to more than 30 countries and had fatality rate of nearly 10%. The SARS genome encodes a number of proteases including papain like protease (PLpro) . Initially, it was reported that SARS PLpro was a deubiquitylase, however subsequent work has shown that PLpro is preferentially a deISGylase. PLpro cleaves ISG15-PLA2 and Ub-PLA2 with high and low efficiency respectively.
Description:
SARS Coronavirus PLPro recombinant protein, with His-tag, expressed in E. coli.
UniProt
P0C6U8
Synonym(s):
papain like protease
Format:
Aqueous buffer solution
Storage / Stability:
Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C.
Application(s):
This enzyme is active in the Ub-CHOP and ISG15-CHOP assay. Suggested Substrate: Ubiquitin-Rhodamine.
Reference(s):
Lindner, H.A., et al., Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease. Arch Biochem Biophys, 2007. 466(1): p. 8-14.
2. Lindner, H.A., et al., The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme. J Virol, 2005. 79(24): p. 15199-208.
3. Barretto, N., et al., The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity. J Virol, 2005. 79(24): p. 15189-98.
2. Lindner, H.A., et al., The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme. J Virol, 2005. 79(24): p. 15199-208.
3. Barretto, N., et al., The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity. J Virol, 2005. 79(24): p. 15189-98.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Deubiquitinase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。