Bpsbioscience/LDN-57444/27706-1/10毫克
商品编号：
27706-1
品牌：
bpsbioscience
市场价：
¥3500.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:397.6Da
CASRegistry#:668467-91-2
Formula:C17H11Cl3N2O3
Description:
LDN-57444isacellpermeableubiquitinC-terminalhydrolase(UCH-L1)inhibitor(Ki=0.4μM).Decreasesproteasomeactivityandincreaseslevelsofubiquitinatedproteins.Inducesapoptosisandcausesdramaticalterationsinsynapticproteindistributionandspinemorphologyinvivo.LDN-57444isausefultooltostudyUCH-L1indifferentpathologicalconditionssuchascancerandneurodegeneration.
Synonym(s):
1H–Indole–2,3–dione,5–chloro–1–[(2,5–dichlorophenyl)methyl]–,3–(O–acetyloxime)
Purity:
≥98%byTLC.
Solubility:
SolubleinDMSO(20mg/ml)
Format:
Yellowpowder
Storage/StABIlity:
Storeat+4°C.Stableassuppliedforupto2yearswhenstoreddessicatedat+4°C.Storesolutionsat-20°Cforupto1week.
Application(s):
UsefulfortheinhibitionofUbiquitinC-terminalHydrolase(UCH-L1)indrugdiscoverystudies.
Reference(s):
1.Tan,etalEndoplasmicreticulumstresscontributestothecelldeathinducedbyUCH-L1inhibitor.Mol.Cell.Biochem.318:109(2008).
2.Susor,A.,etal.,ProteomicanalysisofporcineoocytesduringinvitromaturationrevealsessentialrolefortheubiquitinC-terminalhydrolase-L1.Reprod.134:559-568,(2007).
2.Susor,A.,etal.,ProteomicanalysisofporcineoocytesduringinvitromaturationrevealsessentialrolefortheubiquitinC-terminalhydrolase-L1.Reprod.134:559-568,(2007).
Warning(s):
Protectfrommoisture.Avoidfreeze/thawcycles.
ScientificCategory:
UbiquitinEnzymes
ProductType:
Inhibitors/Activators
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
