Bpsbioscience/Lactacystin/27705/
200 µg
商品编号：
27705
品牌：
bpsbioscience
市场价：
¥7000.00
美元价：
4200.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:376.4Da
CASRegistry#:133343-34-7
Formula:C15H24N2O7S
Description:
Lactacystinisacell-permeable,potentandselectiveproteasomeinhibitorthatbindsirreversIBLytothecatalyticbeta-subunitofthe20Sproteasomeinhibitingitschymotrypsin-likeandtrypsin-likeactivities.AlsoknowntoinhibitNF-kappaBactivation(IC50=10μM).
Synonym(s):
N–Acetyl–S–[(3S,4R)–3–hydroxy–2–[(1S)–1–hydroxy–2–methylpropyl]–4–methyl–5–oxo–D–prolyl]–L–cysteine
Purity:
>99%byTLC.
Solubility:
SolubleinWater(10mg/ml)orDMSO(20mg/ml)
Format:
Whitepowder
Application(s):
Usefulforinhibitionofthe20Sproteasome.
Reference(s):
1.Fenteany,etal.Inhibitionofproteasomeactivitiesandsubunit-specificamino-terminalthreoninemodificationbylactacystin.Science1995,268:726.
2.Kozlowski,L.etal.LactacystininhibitscathepsinAactivityinmelanomacelllines.TumourBiol.2001,22:211.
3.Pasquini,L.A.etal.Lactacystin,aspecificinhibitoroftheproteasome,inducesapoptosisandactivatescaspase-3inculturedcerebellargranulecells.J.NeurosciRes.2000,59:601.
2.Kozlowski,L.etal.LactacystininhibitscathepsinAactivityinmelanomacelllines.TumourBiol.2001,22:211.
3.Pasquini,L.A.etal.Lactacystin,aspecificinhibitoroftheproteasome,inducesapoptosisandactivatescaspase-3inculturedcerebellargranulecells.J.NeurosciRes.2000,59:601.
Warning(s):
Protectfromlight.Protectfrommoisture.Avoidfreeze/thawcycles.
ScientificCategory:
UbiquitinEnzymes
ProductType:
Inhibitors/Activators
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
