Bpsbioscience/Thalidomide/27721-2/500 mg
商品编号：
27721-2
品牌：
bpsbioscience
市场价：
¥4300.00
美元价：
2580.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:258.2Da
CASRegistry#:50-35-1
Formula:C13H10N2O4
Description:
Thalidomideisateratogen,sedative-hypnoticwithinherentanti-inflammatoryproperties.Aselectiveinhibitoroftumornecrosisfactorβ(TNF-β)synthesis.BindstotheE3ubiquitinligasecomplexformedbetweencereblon(CRBN),damagedDNAbindingprotein1(DDB1),andCul4Ainhibitingligaseactivity.InhibitsFGF-inducedangiogenesis.ThalidomideinitiatesitsteratogeniceffectsbybindingtoCRBNandinhibitingtheassociatedubiquitinE3ligaseactivity.Cellpermeable.
Synonym(s):
N–(2,6–dioxo–3–piperidinyl)phthalimide
Purity:
>98%byTLC.
Solubility:
SolubleinDMSO(25mg/ml)
Format:
Whitepowder
Storage/StABIlity:
Storeat+4°C.Stableassuppliedforupto2yearswhenstoreddessicatedat+4°C.Storesolutionsat-20°Cforupto2months.
Application(s):
UsefulforinhibitionofE3ubiquitinligaseenzymes
Reference(s):
1.ItoTetal.Teratogeniceffectsofthalidomide:molecularmechanisms.CellMolLifeSci.2011May;68(9):1569-79.
2.ItoTetal.IdentificationofaPrimaryTargetofThalidomideTeratogenicity.Science,2010.327(5971):1345-1350.
2.ItoTetal.IdentificationofaPrimaryTargetofThalidomideTeratogenicity.Science,2010.327(5971):1345-1350.
Warning(s):
Caution:Teratogen.Protectfrommoisture.
ScientificCategory:
Protease
ProductType:
Inhibitors/Activators
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
