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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/DPP4, His-tag/80040/10 µg
商品详细Bpsbioscience/DPP4, His-tag/80040/10 µg
Bpsbioscience/DPP4, His-tag/80040/10 µg
Bpsbioscience/DPP4, His-tag/80040/10 µg
商品编号: 80040
品牌: bpsbioscience
市场价: ¥8700.00
美元价: 5220.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:87kDA
Genbank#:NM_001935
Tag(s):C-terminalHis-tag
a.a:29–end
Background:
Dipeptidylpeptidase-4(DPP4protein),alsoknownasadenosinedeaminasecomplexingprotein2,isaserineexopeptidasethatcleavesX-prolinedipeptidesfromtheN-terminusofpolypeptides.TheDPP4proteinplaysakeyroleinglucosemetabolism,immuneregulation,signaltransductionandapoptosis.
Description:
HumanDPP4(GenBankAccessionNo.NM_001935),(aminoacids29-end)withC-terminalHistag,MW=87kDa,expressedinaBaculovirusinfectedSf9cellexpressionsystem.
UniProt
P27487
Synonym(s):
DPPIV,CD26,Dipeptidylpeptidase4,ADCP2,DPP4protein
SpecificActivity:
8000pmol/min/µg
AssayConditions:
10mMTris-HCl,pH7.4,10mMMgCl2,0.05%Tween20,and20μMDPPsubstrate1.Incubatefor15minutesatroomtemperature.Fluorescenceintensityismeasuredatexc360/em460.
Formulation:
45mMTris-HClpH8.0,124mMNaCl,2.4mMKCl,225mMImidazoleand10%glycerol
Format:
Aqueousbuffersolution
Storage/StABIlity:

>6monthsat-80°C.

Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):

1.DeaconCF,CarrRD,andHolstJJFrontBiosci.2008Jan1;13:1780-94.
2.LangleyAK,SuffolettaTJ,andJenningsHRPharmacotherapy.2007Aug;27(8):1163-80.

ApplicationReference(s):
1. ZY15557,anovel,longactinginhibitorofdipeptidylpeptidase-4,forthetreatmentofType2diabetesmellitus(2017)
2.Theactivityofcirculatingdipeptidylpeptidase-4isassociatedwithsubclinicalleftventriculardysfunctioninpatientswithtype2diabetesmellitus(2013)

Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Protease
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。