Bpsbioscience/PARP2,GST标签/80502/10µg
商品编号:
80502
品牌:
bpsbioscience
市场价:
¥9300.00
美元价:
5580.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species: Human
Host Species: Sf9 insect cells
MW: 92 kDa
Genbank #: NM_005484
Tag(s): N-terminal GST-tag
a.a: 2–583
Description:
Human PARP2 (GenBank Accession No. NM_005484), a.a. 2-583 with N-terminal GST-tag, MW = 92 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
UniProt
Q9UGN5
Synonym(s):
poly (ADP-ribose) polymerase 2, poly(ADP-ribosyl)transferase 2, ADPRT, PARP2
Unit Definition:
One unit of PARP incorporates 100 pmoles of poly(ADP) in 1 minute from NAD into the acid-insoluble form.
Assay Conditions:
Enzyme reaction is conducted using
BPS's PARP2 Assay Kit (Catalog #80552) at room temperature for 1 hour.
Formulation:
40 mM Tris-HCl, pH 8.0,
110 mM NaCl, 2.2 mM KCl, 16 mM
glutathione, 20% glycerol, and 3 mM DTT.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at -80°C.
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Jha, R., et al., Fertil. Steril. 91 (3), 782-790 (2009).
2. Quenet, D., et al., FASEB J. 22 (11), 3853- 3865 (2008).
Application References:
1. BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency
(2013)
2. Fragment-based ligand design of novel potent inhibitors of tankyrases
(2013)
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
PARP
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。