Bpsbioscience/活化DNA（5x）/80605/500µL
商品编号：
80605
品牌：
bpsbioscience
市场价：
¥2500.00
美元价：
1500.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
PARPisfoundinthecell’snucleus.Themainroleistodetectandsignalsingle-strandDNAbreaks(SSB)totheenzymaticmachineryinvolvedintheSSBrepair.PARPactivationisanimmediatecellularresponsetometabolic,chemical,orrADIation-inducedDNASSBdamage.OncePARPdetectsaSSB,itbindstotheDNA,and,afterastructuralchange,beginsthesynthesisofapoly(ADP-ribose)chain(PAR)asasignalfortheotherDNA-repairingenzymessuchasDNAligaseIII(LigIII),DNApolymerasebeta(pol?),andscaffoldingproteinssuchasX-raycross-complementinggene1(XRCC1).Afterrepairing,thePARchainsaredegradedviaPoly(ADP-ribose)glycohydrolase(PARG).BothPARP-1andPARP-2areactivatedbyDNAsingle-strandbreaks.
Description:
ActivatedDNA(5x)forPARPassay,forusewithBPS"sassaykitsforPARPs1,2,3,and6.PARP1ChemiluminescentAssayKit,#80551;PARP2ChemiluminescentAssayKit,#80552;PARP3ChemiluminescentAssayKit,#80553;PARP6ChemiluminescentAssayKit,#80556;PARP2HomogeneousAssayKit,#80702
Synonym(s):
DNA,PARPsubstrate
SuppliedAs:
Aqueousbuffersolution
Format:
Aqueousbuffersolution
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected
Application(s):
SuitableforusewithBPS"sassaykitstoscreenforinhibitorsofPARPs1,2,3,and6,orforactivatingPARP-1orPARP-2enzymesinvitro.
Reference(s):
1.Dantzer,F.,etal.MethodsEnzymol.2006;409:493-510.
Notes:
BiotinylatedNADcanbeusedforinsitulabelingtostudythecellularlocalizationandtissuedistributionofADP-ribosylatedproteins.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
PARP
ProductType:
Substrate
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
