Bpsbioscience/Roflumilast/27645-3/50 mg
商品编号：
27645-3
品牌：
bpsbioscience
市场价：
¥9900.00
美元价：
5940.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:403.21Da
CASRegistry#:162401-32-3
Formula:C17H14Cl2F2N2O3
Target:PDE4
Background:
TheenzymePDE-4isfoundmainlyininflammatorycells,andRoflumilastactsasaselective,long-actinginhibitorofPDE-4.Ithasanti-inflammatoryeffectsandisunderdevelopmentasanorallyadmiNISTereddrugforthetreatmentofinflammatoryconditionsofthelungssuchasasthma,chronicbronchitis,andchronicobstructivepulmonarydisease(COPD).Invitrostudiesshowthatroflumilastinhibitstheproductionofinflammatorymediatorsinavarietyofhumanimmunecells,suggestingaroleforreducingCOPD-relatedinflammation.Roflumilastisalsofoundtodecreaseglucoselevelsinpatientswithnewlydiagnosedtype-2diabetessincediabetesisanimportantcomorbidityassociatedwithCOPD.
Description:
Roflumilastisanorallyactive,selectiveinhibitorofphophodiesterase-4(PDE-4)withIC50valueof0.11nM.Roflumilastdisplaysanti-inflammatoryandimmunomodulatoryinvitro.
Synonym(s):
Daxas;Daliresp;3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
TashkinDP.ExpertOpinPharmacother.2014Jan;15(1):85-96.
ScientificCategory:
PDEInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
