Bpsbioscience/PDE2A, FLAG-tag/60021/5 µg
商品编号：
60021
品牌：
bpsbioscience
市场价：
¥8800.00
美元价：
5280.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: Sf9 insect cells
MW: 106 kDa
Genbank #: NM_002599
Tag(s): N-terminal FLAG-tag
a.a: 2–941
Description:
Human PDE2A1 (GenBank Accession No. NM_002599), a.a. 2-941, with N-terminal FLAG-tag, MW=106 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
UniProt
O00408
Synonym(s):
PDE2A, phosphodiesterase 2A
Specific Activity:
≥ 7577 pmol/min/μg
Assay Conditions:
10 mM Tris-HCl, pH
7.4, 10 mM MgCl2, 0.05% Tween-20,
200 μM cAMP, and PDE2A1 at 37ºC for
20 min. Quantified by 5-nucleotidase
cleaving the 5-AMP product and
releasing the phosphate group which is
detected by Malachite Green Reagent.
Formulation:
45 mM Tris-HCl, pH 8.0,
124 mM NaCl, 2.4 mM KCl, 90 µg/ml FLAG
peptide, 10% glycerol, and 3 mM DTT.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at -80°C.
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Seybold, J., et al., Blood 105 (9), 3569- 3576 (2005).
2. Martinez, S.E., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (20), 13260-13265 (2002).
Application Reference(s):
1. Design and optimization of purine derivatives as in vivo active PDE10A inhibitors (2017)
2. Pharmacological characterization of a novel potent, selective, and orally active phosphodiesterase 2A inhibitor, PDM-631 (2017)
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
PDE
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
