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ApplicationReference(s):
1. DiscoveryofaNovelSeriesofPyrazolo[1,5-a]pyrimidine-BasedPhosphodiesterase2AInhibitorsStructurallyDifferentfromN-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide(TAK-915),fortheTreatmentofCognitiveDisorders (2017)
2. UtilityofAdenosineMonophosphateDetectionSystemforMonitoringtheActivitiesofDiverseEnzymeReactions (2017)
3. DesignandSynthesisofNovelandSelectivePhosphodiesterase2(PDE2a)InhibitorsfortheTreatmentofMemoryDisorders (2017)
4. DiscoveryofSelectivePhosphodiesterase1InhibitorswithMemoryEnhancingProperties (2017)
5. IdentificationandcharacterizationofapotentandBIOLOGically-activePDE4/7inhibitorviafissionyeast-basedassays (2017)
6. NovelN-hydroxybenzamidesincorporating2-oxoindolinewithunexpectedpotenthistonedeacetylaseinhibitoryeffectsandantitumorcytotoxicity. (2017)
7.Geneticdeletionandpharmacologicalinhibitionofphosphodiesterase10Aprotectsmicefromdiet-inducedobesityandinsulinresistance(2014)
8.Ayeast-basedchemicalscreenidentifiesaPDEinhibitorthatelevatessteroidogenesisinmouseLeydigcellsviaPDE8andPDE4inhibition(2013)
9.Thenovelphosphodiesterase10AinhibitorTHPP-1hasantipsychotic-likeeffectsinratandimprovescognitioninratandrhesusmonkey(2013)
