Bpsbioscience/TPM3-TRKA Mutant, GST-Tag/79080/10 μg
商品编号:
79080
品牌:
bpsbioscience
市场价:
¥7300.00
美元价:
4380.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:125kDa
Genbank#:TPM3:NM_152263,TRKA:NM_002529
Tag(s):N-TerminalGST-Tag
a.a:TPM3:1-258,TRKA:399-end
Background:
TRKAisamemberoftheneurotrophictyrosinekinasereceptor(NTKR)familywhichisamembrane-boundreceptorthat,uponneurotrophinbinding,phosphorylatesitselfandmembersoftheMAPKpathway.TRKAhasacrucialroleinthedevelopmentandfunctionofthenociceptivereceptionsystemaswellasestablishmentofThermoregulationviasweatinginhumans.Theoncogenicrearrangementof5′TPM3-3′NTRK1fusiongenehasbeenfoundinpapillarythyroidcarcinomas.
Description:
HumanTPM3-TRKAfusionprotein,TPM3GenBankAccessionNo.NM_152263,a.a.1-258,TRKAGenbankAccessionNo.NM_002529,a.a.399-end,expressedinanE.coliexpressionsystem.TMP3-TRKAMW=105kDa.
Synonym(s):
TRKA,TPM3,TPM3TRKAmutant,NTKR
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,10mMglutathione,0.1mMEDTA,0.25mMDTT,0.1mMPMSF,25%glycerol.
Storage/StABIlity:
Storeproductat–80°C.Foroptimalstorage,aliquottargetintosmallerquantitiesaftercentrifugationandstoreatrecommendedtemperature.Formostfavorableperformance,avoidrepeatedhandlingandmultiplefreeze/thawcycles.
Application(s):
KinaseAssay
Reference(s):
1.Smeyne,R.J.et.al:SeveresensoryandsympatheticneuropathiesinmicecarryingadisruptedTrk/NGFreceptorgene.Nature368:246-249,1994.
2.MartaG.B.et.al:ASequenceAnalysisoftheGenomicRegionsInvolvedintheRearrangementsbetweenTPM3andNTRK1GenesProducingTRKOncogenesinPapillaryThyroidCarcinomas.Genomics,Volume28,Issue1,1July1995,Pages15–24
ScientificCategory:
Kinase
ProductType:
ReceptorTyrosine
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品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。