Bpsbioscience/DNA聚合酶γ(POLG),His标志标签/21001/100µg
商品编号:
21001
品牌:
bpsbioscience
市场价:
¥7000.00
美元价:
4200.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:141kDa
Genbank#:NM_002693
Tag(s):N-terminalHis-FLAG-tag
a.a:2–1239(end)
Background:
POLGisthecatalyticsubunitofthemitochondrialDNApolymerase.Thecatalyticsubunitcontainsthreeenzymaticactivities,aDNApolymeraseactivity,a3’-5’exonucleaseactivitythatproofreadsmisincorporatednucleotides,anda5’-dRPlyaseactivityrequiredforbaseexcisionrepair.MutationsinthePOLGgeneareassociatedwithseveralmitochondrialdiseases,includingAlpers"disease,ataxia-neuropathydisorders,anddominantandrecessiveformsofprogressiveexternalophthalmoplegia.
Description:
HumanDNApolymeraseγ(gamma),alsoknownasPolgammaandPOLG(GenBankAccessionNo.NM_002693),a.a.2-1239(end),withN-terminalHis-tagandN-terminalFLAG-tag,MW=141kDa,expressedinabaculovirusinfectedSf9cellexpressionsystem.
Synonym(s):
DNApolymerasegamma,Polgamma,POLG
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,80µg/mlFLAGpeptide,0.04%Tween-20,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
UsefulforDNAsynthesisandDNArepair,asanantigenforWesternblotting,andforinhibitorscreening.
Reference(s):
1.Ropp,P.A.,andCopeland,W.C.,Genomics1996;36(3):449-458.
2.Lestienne,P.,Biochem.Biophys.Res.Comm.1987;146(3):1146-1153.
ApplicationReference(s):
1.IdentificationofmechaNISTicallydistinctinhibitorsofHIV-1reversetranscriptasethroughfragmentscreening(2015)
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
MolecularBIOLOGy
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。