Bpsbioscience/ND-630/27071-2/5毫克
商品编号：
27071-2
品牌：
bpsbioscience
市场价：
¥7200.00
美元价：
4320.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:569.63
CASRegistry#:1434635-54-7
Formula:
C28H31N3O8S
Description:
ND-630(NDI010976)isahighlyspecific,reversIBLeinhibitorofACC1(IC50=2nM)andACC2(IC50=6nM).ND-630interactswithintheACCphosphopeptideacceptoranddimerizationsitetopreventdimerizationofACC.Becausethedimerizationsiteisnotconservedamongothermammaliancarboxylases,ND-630lackstheABIlitytoinhibitothermechaNISTically-relatedenzymes.Inratswithdiet-inducedobesity,ND-630reducedhepaticsteatosis,improvedinsulinsensitivity,andreducedweightgain,suggestingACCinhibitionmaybeusefulintreatingmetabolicdisorders,includingtype2diabetesmellitus,andfattyliverdisease.
Synonym(s):
ND630ACC1ACC2
Storage/Stability:
Storeat-20°Cforuptoayear.DissolveinanhydrousDMSOandstoreDMSOstocksolutionsat4°Cforacoupleofdaysorstorestocksolutionsat-20°Cinaliquotsforuptoamonth.Avoidfreeze/thawcyclesofsolutions.
Reference(s):
1.Harriman,G.,etal.,PNAS.2016;113(13):E1796-E1805.
ScientificCategory:
MetabolicEnzymes
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
