Bpsbioscience/Human PKM2，His标签/50295/20µg
商品编号：
50295
品牌：
bpsbioscience
市场价：
¥9600.00
美元价：
5760.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:58.9kDa
Genbank#:NM_002654
Tag(s):N-terminalHis-tag
a.a:fulllength
Background:
PKM1andPKM2aredifferentsplicingproductsofthePKMgene(exon9forPKM1andexon10forPKM2).TheM1isoform(PKM1)isexpressedinmuscleandbrain,andtheM2isoformisexpressedduringembryogenesis,inADIposetissueandpancreaticislets,andisthepredominantformfoundincancercells.
Description:
HumanPyruvatekinaseM2(PKM2)alsoknownasPKM1/M2,isoforma(GenBankAccessionNo.NM_002654)fulllengthwithN-terminalHis-tag,MW=58.9kDa,expressedinanE.coliexpressionsystem.
UniProt
P14618
Synonym(s):
pyruvatekinasemuscle,PKM2,cytosolicthyroidhormone-bindingprotein,CTHBP,thyroidhormone-bindingprotein1,THBP1,opa-interactingprotein3,OIP3
SpecificActivity:
≥200,000pmoles/min/µg.
AssayConditions:
A50μlPKM2reactionisconductedinabuffercontaining50mMTris(pH7.4),10mMMgCl2,50mMKCl,2mMADP,10mMphosphoenolpyruvate(PEP)atroomtemperaturefor15min.ATPproductionisdetectedusingKinase-Glo®LuminescentKinaseAssayPlatform.
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,3mMDTT,20%glycerol,and200mMimidazole
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat–80°C
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Chen,J.,etal.Oncogene(2011)inpress.
2.WongT.S.etal.,Int.J.Cancer123(2),251-257(2008).
3.ChristofkH.R.etal.,Nature452(7184),181-186(2008).
2.WongT.S.etal.,Int.J.Cancer123(2),251-257(2008).
3.ChristofkH.R.etal.,Nature452(7184),181-186(2008).
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
MetabolicEnzymes-Kinase
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
